High-sensitivity, multiplexed biomarker detection platforms engineered for clinical validation, translational research, and companion diagnostics. Fully integrated with AI-driven analytical pipelines.
Aevum Zenth Health Sciences delivers a comprehensive suite of biomarker assays spanning proteomics, metabolomics, genomics, and digital pathology. Our platforms utilize proprietary immunoassay architectures, microfluidic sample preparation, and machine learning-optimized validation to deliver unmatched signal-to-noise ratios and reproducibility.
From early-phase biomarker discovery to FDA-cleared companion diagnostics, our assays are built on CLIA/CAP-certified infrastructure with full LIMS integration and automated data export to standard clinical reporting formats.
Modular detection platforms optimized for specific biomarker classes and sample matrices.
Sandwich ELISA, electrochemiluminescence (ECLIA), and magnetic bead-based multiplex panels for cytokines, growth factors, and therapeutic drug monitoring.
ctDNA methylation profiling, cfDNA fragmentomics, exosome isolation, and circulating tumor cell (CTC) enumeration for early detection and minimal residual disease monitoring.
Mass spectrometry-ready sample prep kits, targeted protein arrays, and untargeted metabolic profiling with standardized internal controls and normalization algorithms.
qPCR, ddPCR, NGS library prep, RNA-seq optimization, and gene fusion detection with built-in QC metrics and bioinformatics-ready output formats.
Automated tissue staining, whole-slide imaging integration, quantitative IHC scoring, and AI-powered morphometric analysis for oncology and immunology biomarkers.
Machine learning models for assay calibration, outlier detection, batch effect correction, and automated regulatory documentation generation for FDA/EMA submissions.
| Metric | Standard Assay | High-Sensitivity (HS) Panel | Point-of-Care (POC) Rapid |
|---|---|---|---|
| Limit of Detection (LOD) | 0.5 - 5.0 pg/mL | < 0.1 pg/mL | 5 - 20 pg/mL |
| Dynamic Range | 4 logs | 5.2 logs | 2.8 logs |
| Intra-Assay CV | < 8% | < 4.5% | < 12% |
| Inter-Assay CV | < 10% | < 6% | < 15% |
| Sample Volume | 50 µL | 10 µL | 20 µL |
| Automation Level | 96/384-well robotic | Fully closed microfluidic | Manual/Semi-auto |
Barcoded specimen receipt, chain-of-custody verification, and automated metadata capture into our cloud-native LIMS. Supports serum, plasma, whole blood, FFPE, CSF, and urine.
Robotic liquid handling with closed-system microfluidics. Nuclease-free processing, spike-in controls, and matrix-matched calibration standards.
Parallel multiplex detection across selected modalities. Real-time kinetic monitoring, temperature regulation, and optical/magnetic readout.
Automated outlier rejection, batch normalization, hook-effect detection, and reference range mapping against population datasets.
HIPAA/GDPR-compliant PDF/FHIR output, HL7 v2/v3 messaging, API endpoints for EHR integration, and raw data export for independent verification.
Whether you're developing companion diagnostics, running phase II/III trials, or optimizing routine clinical testing, our assay teams provide co-development support, validation studies, and dedicated technical account management.