Stage
Modality
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AZN-409 Phase III

SynapVance

Alzheimer's Disease (Early-Onset)

Patients
1,240
Sites
87
Anti-Tau IV Infusion CNS Penetration
AZN-312 Phase II

DopamireTM

Parkinson's Disease (Non-Motor Symptoms)

Patients
480
Sites
34
Oral D2 Agonist QD Dosing
AZN-227 Phase I

NeuroSilence

Amyotrophic Lateral Sclerosis (ALS)

Patients
112
Sites
18
Intrathecal SOD1/TDP-43 Lipid NP
AZN-104 Commercial

NeuraRelief

Diabetic Peripheral Neuropathy

Prescriptions
2.4M+
Markets
28
Oral Na+ Channel Block BID Dosing
AZN-518 Preclinical

CerebriGene

Huntington's Disease

Models
4
Vector
AAV9
CRISPR-Cas9 In Vivo Intracranial
AZN-334 Phase II

NeuroStimPro

Treatment-Resistant Depression

Patients
210
Sites
15
Closed-Loop DBS AI-Adaptive

Pipeline Distribution

3
Preclinical
5
Phase I
8
Phase II
4
Phase III
2
Commercial

Research & Innovation

🧠

Blood-Brain Barrier Delivery

Proprietary lipid nanoparticle and focused ultrasound platforms enabling precise CNS drug delivery with >400% increased penetration efficiency.

🦨

Digital Biomarkers

Wearable-integrated AI tracking motor, cognitive, and speech patterns to accelerate clinical trial endpoints by up to 60%.

🦠

Organoid Modeling

Patient-derived cerebral organoids for rapid toxicology screening and disease modeling across neurodegenerative indications.