Research Focus

Core Scientific Pillars

Cross-disciplinary teams engineered to accelerate breakthroughs from bench to bedside.

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Precision Gene Editing

Base editing and prime editing platforms targeting monogenic disorders with single-nucleotide resolution.

In Vivo DeliveryHDR-Free
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Epigenetic Modulation

CRISPR-off/on systems for reversible transcriptional control without altering underlying DNA sequence.

dCas9-FusionTherapeutic Windows
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Multi-Omics Integration

Unified genomic, transcriptomic, and proteomic datasets enabling patient stratification for rare diseases.

Single-CellBiomarker Discovery
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Neural Tissue Engineering

3D-bioprinted neuroscaffolds seeded with patient-derived iPSCs for Parkinson's and spinal cord injury models.

VascularizationMatrigel-Free
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Cardiac Patch Therapies

Engineered myocardial constructs expressing connexin-43 to restore synchronicity post-MI.

BioresorbableClinical Readiness
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AI-Driven Drug Design

Generative protein models accelerating lead optimization and de novo enzyme design for novel targets.

Diffusion ModelsDocking Prediction
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In Silico Clinical Trials

Digital twin populations simulating pharmacokinetic/pharmacodynamic profiles to reduce Phase I attrition.

PBPK ModelingAdaptive Design
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Next-Gen CAR-T

Armored CAR constructs with IL-12 secretion and PD-1 blockade for solid tumor microenvironment penetration.

Tumor AgnosticAllogeneic
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Gut-Brain Axis Therapeutics

Engineered probiotic consortia delivering neuroactive metabolites across the BBB for mood disorders.

Synthetic BiologyOral Delivery
Development Pipeline

Clinical & Preclinical Programs

Rigorously tracked therapeutic candidates progressing through regulated development pathways.

Program CodeTherapeutic AreaMechanismStatusTarget
ZB-7042OncologyBi-specific T-cell EngagerPhase IIIMetastatic NSCLC
ZB-8811NeurologyAntisense OligonucleotidePhase IIALS / SMA
ZB-5509ImmunologyJAK-STAT InhibitorPhase IAuimmune Hepatitis
ZB-3320MetabolicGut Microbiome ModulatorPreclinicalType 2 Diabetes
ZB-9105CardiologyExosome-Delivered miRNAPhase IIHeart Failure (HFrEF)
Knowledge & Data

Recent Publications & Open Data

Advancing scientific transparency through open-access research and curated datasets.

In Vivo Prime Editing Corrects Pathogenic Variants in a Mouse Model of Duchenne Muscular Dystrophy

Journal of Gene Medicineβ€’Oct 2024β€’DOI: 10.1002/igm.2024.089

Multi-Scale Modeling of Tumor Microenvironment Heterogeneity Using Graph Neural Networks

Nature Computational Scienceβ€’Aug 2024β€’DOI: 10.1038/s43588-024-00512

Zenth Bio Open Dataset: 10K Single-Cell Transcriptomes from Treatment-Resistant Depression Cohorts

BioRxiv Preprintβ€’Jun 2024β€’CC-BY 4.0
Infrastructure

Global Research Network

State-of-the-art facilities enabling 24/7 translational research across time zones.

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Neo Geneva
Core Discovery & Genomics
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San Francisco Bay
AI Drug Design & CompBio
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Cambridge, UK
Regenerative Medicine
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Tokyo
Immunology & Cell Therapy
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Singapore
Microbiome & Tropical Disease

Academic & Industry Partnerships

Propose joint research, licensing opportunities, or clinical trial collaborations.

All submissions are reviewed by our Scientific Advisory Board within 10 business days. Confidentiality agreements available upon request.